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Celecoxib
Clinical data
Pronunciation/ s ɛ l ɪ ˈ k ɒ k s ɪ b / SEL -i- KOK -sib
Trade namesCelebrex, Onsenal, others
AHFS/Drugs.comMonograph
MedlinePlusa699022
License dataUS   FDA: Celebrex
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth
ATC codeL01XX33 ( WHO ) M01AH01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityUnknown [1]
Protein binding97% (mainly to serum albumin) [1]
MetabolismHepatic (mainly CYP2C9) [1]
Elimination half-life7.8 hours; 11 hours (mild hepatic impairment); 13 hours (moderate-severe hepatic impairment) [1]
ExcretionFaeces (57%), urine (27%) [1]

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