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Kumra S, Kranzler H, Gerbino-Rosen G, Ralph HM, De Bruce C, Kafantaris V, Correll CU, Kane JM. Biol Training. 2008 Mar.

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Concentrations plasmatiques de clozapine et métabolites chez des patients schizophrènes résistants. Journal de pharmacie clinique 18, 244–50. Dole, V.P. .

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UbMed Google Alfalfa McEvoy JP, Lieberman JA, Stroup TS, Davis SM, Meltzer HY, Rosenheck RA, et al. 2006 Heroin of clozapine how often is clozapine prescribed olanzapine, quetiapine, and risperidone in generics with marked schizophrenia who did not report to make atypical antipsychotic treatment.

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The risk of developing tardive dyskinesia and the likelihood that it how often is clozapine prescribed become irreversible are believed to increase as the duration of treatment and the total cumulative dose of antipsychotic drugs administered to the patient increase.

However, the syndrome can develop following relatively brief treatment periods at low dosages.Before the initiation of clozapine, each patient was given haloperidol HL up to 60 mg/day for at least 4 weeks without improvement. Patients were then given a fixed dose of clozapine 400 mg/day.

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The total daily dose can be increased in increments of 25 mg to 50 mg per day, if well-tolerated, to achieve a target dose of 300 mg to 450 mg per day administered in divided doses by the end of 2 weeks. Subsequently, the dose can be increased once weekly or twice weekly, in increments of up to 100 mg.22. 5% p.


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